Special Seminar Announcement, 10/18/2005

[Co-sponsored by the Biomedical, Chemical Engineering Departments and the Levich Institute]

Tuesday, 10/18/2005
2:00 PM
Steinman Hall, Room #312
(Chemical Engineering Conference Room)

Professor James Grotberg
University of Michigan
Department of Biomedical Engineering

"Biofluid Mechanics in Lungs and Lung Devices"


Biofluid mechanics in the pulmonary system involves multiphase flow phenomena of air-liquid interfaces, surfactants, moving walls, flexible boundaries and a wide range of relevant dimensionless parameter values. This overview of research in our group will include aspects of liquid and surfactant delivery into the lung for purposes of treating hyaline membrane disease of prematurely-born infants and for liquid ventilation, a process of breathing with the lung filled by perfluorocarbon liquid. Dynamics of surface film propagation of surfactant as well as liquid plug propagation in the airways will be discussed in view of both animal and benchtop experiments and related theory. Finally, gas transport in an implantable artificial lung, driven by the heart, will be analyzed for optimizing oxygen and carbon dioxide exchange while minimizing the pressure drop across the bundle of microfibers which make up the device.

James B. Grotberg, Ph.D., M.D. is a Professor in the Department of Biomedical Engineering and the Department of Surgery at The University of Michigan. He is a Fellow of the American Institute for Medical and Biological Engineering, the American Physical Society's Division of Fluid Dynamics, and an Inaugural Fellow of the Biomedical Engineering Society. He is currently an Associate Editor for Physics of Fluids and past Associate Editor of J Biomechanical Engineering and Annual Review of Fluid Mechanics. He has held an RCDA from NIH and a Presidential Young Investigator Award from NSF. Dr. Grotberg is the Director of the new University of Michigan-NASA Biosience and Engineering Institute. He is also a licensed physician with many years of clinical experience in emergency and critical care medicine.